Fabrication of 45s5 Bioactive Glass-polycaprolactone Composite Scaffolds
نویسندگان
چکیده
Tissue engineering is a multi-disciplinary field, which aims to apply innovative biomaterials to replace or restore ill or damaged tissues of the human body, such as skin and bones. In particular, porous scaffolds are used as temporary 3D templates to support cell attachment and proliferation during the spontaneous regeneration of natural tissues and this approach is particularly promising for the bone tissue restoration [1, 2].
منابع مشابه
Composites made of flame-sprayed bioactive glass 45S5 and polymers: bioactivity and immediate sealing properties.
AIM To engineer systems using polyisoprene (PI) or polycaprolactone (PCL) and nanometric bioactive glass 45S5 (BG) that could create a hydroxyapatite interface and thus ultimately make the use of an endodontic sealer unnecessary. METHODOLOGY Different composites using PI or PCL as matrix material were prepared with BG contents of up to 30 wt%. Unfilled PI and PCL, commercially available fille...
متن کاملStem Cell Bone Differentiation on Polyol Lactic Acid Composite Nanoparticles Containing 45S5 Bioactive Glass Nanoparticles
Abstract Background and Objectives Now day, using of stem cells and nanoparticles in the differentiation of stem cells is considered as a therapeutic approach. The purpose of this study was to synthesize and characterize nanocomposite polyacrylic polycarboxylic acid containing nanoparticles of biologically active glass 45S5 crushed and assessment effect of this composite on the propagation and...
متن کاملThe Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
Bioglass has been used for bone-filling material in bone tissue engineering, but its lean mechanical strength limits its applications in load-bearing positions. Carbon nanotubes (CNTs), with their high aspect ratio and excellent mechanical properties, have the potential to strengthen and toughen bioactive glass material without offsetting its bioactivity. Therefore, in this research, multiwall ...
متن کاملAn investigation on injectable composites fabricated by 45S5 bioactive glass and gum tragacanth: Rheological properties and in vitro behavior
The injectable composites were formulated from melt-derived 45S5 bioactive glass powder and gum tragacanth. The effect of tragacanth concentration (2 and 4 w/v%) and powder to liquid ratio (P/L= 1.5 to 2.5) on rheological properties, injectability, degradation, swelling, and bioactivity the composites was studied. With the increase of P/L ratio and tragacanth concentration, the force requ...
متن کاملFabrication and Characterization of Polycaprolactone – Zeolite Y Nanocomposite for Bone Tissue Engineering
In recent years, nanoceramics have been used in scaffolds to emulate the nanocomposite with a three-dimensional structure of natural bone tissue. In this regard, polycaprolactone biopolymer is widely used as a scaffold in bone tissue engineering. The goal of this research is to produce porous scaffolds of polycaprolactone - zeolite biocomposite with suitable mechanical, bioactive and biological...
متن کامل